An American spy aircraft on Sunday fired missiles into a Pakistan’s tribal region and killed at least four people, security officials said.


The unmanned drone fired two missiles on a house near Miranshah, headquarters of North Waziristan tribal region.


Identities of the killed are not immediately known. Tribesmen said that the house was destroyed in the strike around 10:50 a.m.


It is second US attack in the same region in less than ten days.


Six people were killed in a US drone strike on September 22. Earlier at least four people were killed when a US drone targeted a house with missiles in North Waziristan on August 31.


The Sunday’s strike was 21 in Pakistan this year, killing at least 117.


The latest strike was carried out just days after Pakistani Prime Minister Nawaz Sharif condemned the American drone strikes in his speech at the UN General Assembly.


Pakistan insists the drone attacks are counterproductive and complicate the war against violent extremism. 

The US has rejected Pakistan’s calls to halt the CIA-controlled drone campaign.