Researchers from two centers of Madrid have developed a vaginal gel for rectal application that prevents spreading the virus that causes AIDS, HIV. The microbicidal ointment, still in the preclinical phase, has shown an efficiency of 85 % in mice, whereas in experiments in vitro protection was 100 % when combined with antiretrovirals. Health experts reported that the drug will take between three and five years to reach the market, provided they get a financial funding for human trials, to confirm the results obtained in animals.
The gel was presented Wednesday by the Gregorio Marañón Hospital authorities and the University of Alcalá de Henares, since 2003 working in various applications or HIV drugs. Maria Angeles Muñoz, head of the Laboratory of Molecular Immunobiology of the clinic, said the microbicide has a protective efficacy of 18 to 24 hours, which may have sexual encounters without contagion. The ointment should be applied at least four to eight hours before intercourse.
Muñoz said microbicide used particles which block infection called dendrimers carbosilianos but not prevent pregnancies, it would be a possibility for HIV-infected men procreate. ” The molecule that we are using does not alter sperm fertility,” Muñoz added.
Javier de la Mata, Professor of the Department of Inorganic Chemistry, University of Alcalá, said the research results have been endorsed by Harvard University in the United States, and that the gel has already been patented at the national and international level.